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The Caspase Pathway as a Possible Therapeutic Target in Experimental Pemphigus

Apoptosis plays a role in pemphigus IgG-dependent acantholysis; theoretically, the blockade of the caspase pathway could prevent the blistering that is caused by pemphigus autoantibodies. Using this strategy, we attempted to block the pathogenic effect of pemphigus IgG in Balb/c mice by using the ca...

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Detalhes bibliográficos
Main Authors: Pacheco-Tovar, Deyanira, López-Luna, Argelia, Herrera-Esparza, Rafael, Avalos-Díaz, Esperanza
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049334/
https://ncbi.nlm.nih.gov/pubmed/21403857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/563091
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