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Llama-derived single-domain antibodies for the detection of botulinum A neurotoxin

Single-domain antibodies (sdAb) specific for botulinum neurotoxin serotype A (BoNT A) were selected from an immune llama phage display library derived from a llama that was immunized with BoNT A toxoid. The constructed phage library was panned using two methods: panning on plates coated with BoNT A...

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Detalhes bibliográficos
Main Authors: Swain, Marla D., Anderson, George P., Zabetakis, Dan, Bernstein, Rachael D., Liu, Jinny L., Sherwood, Laura J., Hayhurst, Andrew, Goldman, Ellen R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049303/
https://ncbi.nlm.nih.gov/pubmed/20582697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-010-3905-3
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