Cholecystokinin knockout mice are resistant to high-fat diet-induced obesity

BACKGROUND & AIMS: Cholecystokinin (CCK) is a satiation peptide released during meals in response to lipid intake; it regulates pancreatic digestive enzymes that are required for absorption of nutrients. We proposed that mice with a disruption in the CCK gene (CCK-KO mice) that were fed a diet o...

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Main Authors: Lo, Chun-Min, King, Alexandra, Samuelson, Linda C, Kindel, Tammy Lyn, Rider, Therese, Jandacek, Ronald J, Raybould, Helen E, Woods, Stephen C, Tso, Patrick
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049264/
https://ncbi.nlm.nih.gov/pubmed/20117110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.01.044
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