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Prenatal Nicotine Exposure Increases GABA Signaling and Mucin Expression in Airway Epithelium

Maternal smoking during pregnancy increases the risk of respiratory disease in offspring, but surprisingly little is known about the underlying mechanisms. Nicotinic acetylcholine receptors (nAChRs) expressed in bronchial epithelial cells (BECs) mediate the effects of nicotine on lung development an...

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Bibliographic Details
Main Authors: Fu, Xiao Wen, Wood, Kelsey, Spindel, Eliot R.
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049233/
https://ncbi.nlm.nih.gov/pubmed/20448051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0109OC
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