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ALLOPURINOL DOES NOT DECREASE BLOOD PRESSURE OR PREVENT THE DEVELOPMENT OF HYPERTENSION IN THE DOCA-SALT RAT MODEL

Reactive oxygen species (ROS) play an important role in the pathogenesis of hypertension, disease in which ROS levels and markers of oxidative stress are increased. Xanthine oxidase (XO) is a ROS-producing enzyme the activity of which may increase during hypertension. Studies on XO inhibition effect...

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Detalhes bibliográficos
Main Authors: Szasz, Theodora, Linder, A. Elizabeth, Davis, Robert P., Burnett, Robert, Fink, Gregory D., Watts, Stephanie W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049193/
https://ncbi.nlm.nih.gov/pubmed/20881613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e3181f80194
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