ALLOPURINOL DOES NOT DECREASE BLOOD PRESSURE OR PREVENT THE DEVELOPMENT OF HYPERTENSION IN THE DOCA-SALT RAT MODEL

Reactive oxygen species (ROS) play an important role in the pathogenesis of hypertension, disease in which ROS levels and markers of oxidative stress are increased. Xanthine oxidase (XO) is a ROS-producing enzyme the activity of which may increase during hypertension. Studies on XO inhibition effect...

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Huvudupphovsmän: Szasz, Theodora, Linder, A. Elizabeth, Davis, Robert P., Burnett, Robert, Fink, Gregory D., Watts, Stephanie W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049193/
https://ncbi.nlm.nih.gov/pubmed/20881613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e3181f80194
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