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Immunization with Amyloid-β Attenuates Inclusion Body Myositis-Like Myopathology and Motor Impairment in a Transgenic Mouse Model

Inclusion body myositis (IBM), the most common muscle disease to afflict the elderly, causes slow but progressive degeneration of skeletal muscle and ultimately paralysis. Hallmark pathological features include T-cell mediated inflammatory infiltrates and aberrant accumulations of proteins, includin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kitazawa, Masashi, Vasilevko, Vitaly, Cribbs, David H., LaFerla, Frank M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049190/
https://ncbi.nlm.nih.gov/pubmed/19439591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1150-09.2009
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