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Muramyl dipeptide induces Th17 polarization through activation of endothelial cells

Endothelial cells express the nucleotide binding oligomerization domain (NOD) receptor 2, which recognizes the bacterial derivate muramyl dipeptide (MDP). MDP stimulation of these cells enhances their IL-6 production and may thus contribute to the immune and inflammatory activities in the skin. Howe...

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Bibliografiska uppgifter
Huvudupphovsmän: Manni, Michela, Ding, Wanhong, Stohl, Lori L., Granstein, Richard D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048901/
https://ncbi.nlm.nih.gov/pubmed/21307291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000847
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