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Tissue distribution and clearance kinetics of non-transferrin-bound iron in the hypotransferrinemic mouse: a rodent model for hemochromatosis.

Genetically hypotransferrinemic mice accumulate iron in the liver and pancreas. A similar pattern of tissue iron accumulation occurs in humans with hereditary hemochromatosis. In both disorders, there is a decreased plasma concentration of apotransferrin. To test the hypothesis that nontransferrin-b...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Craven, C M, Alexander, J, Eldridge, M, Kushner, J P, Bernstein, S, Kaplan, J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304890/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3472216/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.10.3457
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