Chimeric mouse-human IgG1 antibody that can mediate lysis of cancer cells.

A chimeric mouse-human antibody has been created that recognizes an antigen found on the surface of cells from many carcinomas. Immunoglobulin constant (C) domains of the mouse monoclonal antibody L6, C gamma 2a and C kappa, were substituted by the human C gamma 1 and C kappa by recombining cDNA mod...

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Main Authors: Liu, A Y, Robinson, R R, Hellström, K E, Murray, E D, Chang, C P, Hellström, I
格式: Artigo
語言:Inglês
出版: 1987
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC304886/
https://ncbi.nlm.nih.gov/pubmed/3106970
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