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Therapeutic strategies to avoid long term adverse outcomes of neonatal antiepileptic drug exposure

Antiepileptic drugs (AEDs) such as phenobarbital, phenytoin and valproic acid, when given in therapeutic doses to neonatal rats, cause pronounced neuronal apoptotic cell death. This effect is especially pronounced in the striatum and cortex during the second postnatal week; a period corresponding to...

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Auteurs principaux: Forcelli, Patrick A., Janssen, Megan J., Stamps, Lauren A., Sweeney, Cameron, Vicini, Stefano, Gale, Karen
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048842/
https://ncbi.nlm.nih.gov/pubmed/20618394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2010.02603.x
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