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Interferon gamma induces lung colonization by intravenously inoculated B16 melanoma cells in parallel with enhanced expression of class I major histocompatibility complex antigens.

Treatment of H-2-deficient nonmetastatic B16 melanoma cells with physiological doses of interferon gamma (IFN-gamma) reduced cellular growth in vitro but induced a shift to the lung-colonizing phenotype as assessed after intravenous injection of the treated cells. As little as 1 antiviral unit of re...

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Detalles Bibliográficos
Main Authors: Taniguchi, K, Petersson, M, Höglund, P, Kiessling, R, Klein, G, Kärre, K
Formato: Artigo
Idioma:Inglês
Publicado: 1987
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC304879/
https://ncbi.nlm.nih.gov/pubmed/3106968
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