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Bleomycin Hydrolase Is Regulated Biphasically in a Differentiation- and Cytokine-dependent Manner: RELEVANCE TO ATOPIC DERMATITIS
Loss-of-function mutation in the profilaggrin gene is a major risk factor for atopic dermatitis (AD). Previously, we showed that a neutral cysteine protease, bleomycin hydrolase (BH), has a role in generating natural moisturizing factors, and calpain I is an upstream protease in the filaggrin degrad...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048707/ https://ncbi.nlm.nih.gov/pubmed/21190945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.169292 |
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