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Substrate Specificity Overlap and Interaction between Adrenoleukodystrophy Protein (ALDP/ABCD1) and Adrenoleukodystrophy-related Protein (ALDRP/ABCD2)

X-linked adrenoleukodystrophy (X-ALD) is a neurodegenerative disorder caused by mutations in the ABCD1 gene, which encodes a peroxisomal member of the ATP-binding cassette (ABC) transporter subfamily D called ALDP. ALDP is supposed to function as a homodimer allowing the entry of CoA-esters of very-...

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Bibliographische Detailangaben
Hauptverfasser: Genin, Emmanuelle C., Geillon, Flore, Gondcaille, Catherine, Athias, Anne, Gambert, Philippe, Trompier, Doriane, Savary, Stéphane
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048694/
https://ncbi.nlm.nih.gov/pubmed/21209459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.211912
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