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Comparative anatomy of the human APRT gene and enzyme: nucleotide sequence divergence and conservation of a nonrandom CpG dinucleotide arrangement.

The functional human adenine phosphoribosyltransferase (APRT) gene is less than 2.6 kilobases in length and contains five exons. The amino acid sequences of APRTs have been highly conserved throughout evolution. The human enzyme is 82%, 90%, and 40% identical to the mouse, hamster, and Escherichia c...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Broderick, T P, Schaff, D A, Bertino, A M, Dush, M K, Tischfield, J A, Stambrook, P J
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 1987
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304867/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3554238/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.10.3349
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