Lack of Collagen XVIII Long Isoforms Affects Kidney Podocytes, whereas the Short Form Is Needed in the Proximal Tubular Basement Membrane

Collagen XVIII is characterized by three variant N termini, an interrupted collagenous domain, and a C-terminal antiangiogenic domain known as endostatin. We studied here the roles of this collagen type and its variant isoforms in the mouse kidney. Collagen XVIII appeared to be in a polarized orient...

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Bibliographic Details
Main Authors: Kinnunen, Aino I., Sormunen, Raija, Elamaa, Harri, Seppinen, Lotta, Miller, R. Tyler, Ninomiya, Yoshifumi, Janmey, Paul A., Pihlajaniemi, Taina
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Glycobiology and Extracellular Matrices
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048663/
https://ncbi.nlm.nih.gov/pubmed/21193414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.166132
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