Detection of human DNA polymorphisms with a simplified denaturing gradient gel electrophoresis technique.

Single base pair differences between otherwise identical DNA molecules can result in altered melting behavior detectable by denaturing gradient gel electrophoresis. We have developed a simplified procedure for using denaturing gradient gel electrophoresis to detect base pair changes in genomic DNA....

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Noll, W W, Collins, M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304865/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2883652/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.10.3339
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