Prevention of clinical and histological signs of proteolipid protein (PLP)-induced experimental allergic encephalomyelitis (EAE) in mice by the water-soluble carbon monoxide-releasing molecule (CORM)-A1

We have evaluated the effects of the carbon monoxide-releasing molecule CORM-A1 [Na(2)(BH(3)CO(2)); ALF421] on the development of relapsing–remitting experimental allergic encephalomyelitis (EAE) in SJL mice, an established model of multiple sclerosis (MS). The data show that the prolonged prophylac...

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Main Authors: Fagone, P, Mangano, K, Quattrocchi, C, Motterlini, R, Di Marco, R, Magro, G, Penacho, N, Romao, C C, Nicoletti, F
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2011
Assuntos:
Animal Models
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048621/
https://ncbi.nlm.nih.gov/pubmed/21235533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2010.04303.x
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