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Endocytosis Deficiency of Epidermal Growth Factor (EGF) Receptor–ErbB2 Heterodimers in Response to EGF Stimulation

Epidermal growth factor (EGF) stimulates the homodimerization of EGF receptor (EGFR) and the heterodimerization of EGFR and ErbB2. The EGFR homodimers are quickly endocytosed after EGF stimulation as a means of down-regulation. However, the results from experiments on the ability of ErbB2 to undergo...

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Bibliografiske detaljer
Main Authors: Wang, Zhixiang, Zhang, Lianfeng, Yeung, Tai K., Chen, Xinmei
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC30486/
https://ncbi.nlm.nih.gov/pubmed/10233167
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