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In vivo label-free photoacoustic microscopy of cell nuclei by excitation of DNA and RNA

Imaging of cell nuclei plays a critical role in cancer diagnosis and prognosis. In order to image noninvasively cell nuclei in vivo without staining, we developed ultraviolet photoacoustic microscopy (UV-PAM), in which 266-nm-wavelength ultraviolet light excites unlabeled DNA and RNA in cell nuclei...

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Bibliographic Details
Main Authors: Yao, Da-Kang, Maslov, Konstantin, Shung, Kirk K., Zhou, Qifa, Wang, Lihong V.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048585/
https://ncbi.nlm.nih.gov/pubmed/21165116
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