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Induction of heme oxygenase-1 protects against nutritional fibrosing steatohepatitis in mice

BACKGROUND: Heme oxygenase-1 (HO-1), an antioxidant defense enzyme, has been shown to protect against oxidant-induced liver injury. However, its role on liver fibrosis remains unclear. This study aims to elucidate the effect and the mechanism of HO-1 in nutritional fibrosing steatohepatitis in mice....

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Detalhes bibliográficos
Main Authors: Wang, Rong Qi, Nan, Yue Min, Wu, Wen Juan, Kong, Ling Bo, Han, Fang, Zhao, Su Xian, Kong, Li, Yu, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048569/
https://ncbi.nlm.nih.gov/pubmed/21314960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-10-31
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