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Rv0989c encodes a novel (E)-geranyl diphosphate synthase facilitating decaprenyl diphosphate biosynthesis in Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb) has a highly complex cell wall, which is required for both bacterial survival and infection. Cell wall biosynthesis is dependent on decaprenyl diphosphate as a glyco-carrier, which is hence an essential metabolite in this pathogen. Previous biochemical studies indica...

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Hlavní autoři: Mann, Francis M., Thomas, Jill A., Peters, Reuben J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048469/
https://ncbi.nlm.nih.gov/pubmed/21237161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2011.01.007
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