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Identifying Causal Genes and Dysregulated Pathways in Complex Diseases
In complex diseases, various combinations of genomic perturbations often lead to the same phenotype. On a molecular level, combinations of genomic perturbations are assumed to dys-regulate the same cellular pathways. Such a pathway-centric perspective is fundamental to understanding the mechanisms o...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048384/ https://ncbi.nlm.nih.gov/pubmed/21390271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001095 |
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