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Latent Membrane Protein 1, the EBV-encoded oncogenic mimic of CD40, accelerates autoimmunity in B6.Sle1 mice

EBV infection is associated with development of the autoimmune disease systemic lupus erythematosus (SLE), and EBV can reactivate during SLE flares. Latent membrane protein-1 (LMP1) is an EBV-encoded, oncogenic mimic of CD40 that can be re-expressed in PBMCs during SLE flares, as >90% of humans a...

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Detalhes bibliográficos
Main Authors: Peters, Anna L., Stunz, Laura L., Meyerholz, David K., Mohan, Chandra, Bishop, Gail A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048355/
https://ncbi.nlm.nih.gov/pubmed/20810985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0904065
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