Llwytho...

A nonsense mutation causes hereditary goitre in the Afrikander cattle and unmasks alternative splicing of thyroglobulin transcripts.

The hereditary goitre of Afrikander cattle is an autosomal recessive disease characterized in homozygotes by the production of abnormal thyroglobulin (Tg) and the coexistence in the thyroid of normal-sized 8.4-kilobase (kb) Tg mRNA with a misspliced 7.3-kb message having lost exon 9. We have cloned...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ricketts, M H, Simons, M J, Parma, J, Mercken, L, Dong, Q, Vassart, G
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1987
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC304832/
https://ncbi.nlm.nih.gov/pubmed/3472203
Tagiau: Ychwanegu Tag
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