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Quantitative evidence for early life fitness defects from 32 longevity-associated alleles in yeast
Reduced fecundity has been associated with some alleles that enhance longevity in invertebrate and mammalian models. This observation has been suggested to support the antagonistic pleiotropy theory of aging, which predicts that alleles of some genes promoting fitness early in life have detrimental...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048082/ https://ncbi.nlm.nih.gov/pubmed/21191185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.1.14457 |
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