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Cell size and growth rate are major determinants of replicative lifespan

Yeast cells, like mammalian cells, enlarge steadily as they age. Unabated cell growth can promote cellular senescence; however, the significance of the relationship between size and cellular lifespan is not well understood. Herein, we report a genetic link between cell size, growth rate and lifespan...

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Detalles Bibliográficos
Main Authors: Yang, Jingye, Dungrawala, Huzefa, Hua, Hui, Manukyan, Arkadi, Abraham, Lesley, Lane, Wesley, Mead, Holly, Wright, Jill, Schneider, Brandt L
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048081/
https://ncbi.nlm.nih.gov/pubmed/21248481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.1.14455
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