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Pharmacological actions of progestins to inhibit cervical ripening and prevent delivery depend upon their properties, the route of administration and the vehicle

OBJECTIVE: To evaluate cervical changes and delivery at term during pregnancy in rats after various progestin treatments. STUDY DESIGN: Pregnant rats were treated by various routes and vehicles with progesterone (P4), 17-alpha-hydroxyprogesterone caproate (17P), R5020 and RU-486. Delivery time was d...

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Bibliografiske detaljer
Main Authors: Kuon, Ruben J., Shi, Shao-Qing, Maul, Holger, Sohn, Christof, Balducci, James, Maner, William L., Garfield, Robert E.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048062/
https://ncbi.nlm.nih.gov/pubmed/20452487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2010.03.025
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