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Pioglitazone for the treatment of type 2 diabetes in patients inadequately controlled on insulin
Insulin resistance and impaired beta-cell function are primary defects that occur early in the course of development of type 2 diabetes. Insulin resistance leads to hyperinsulinemia in order to maintain normal glucose tolerance. In most cases of type 2 diabetes, beta-cell dysfunction develops subseq...
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Dove Medical Press
2010
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3047993/ https://ncbi.nlm.nih.gov/pubmed/21437092 |
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