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Controversial data on simvastatin in asthma: What about the rat model?

The effects of simvastatin on lung inflammation in asthma are controversial. Reduction of inflammation and hyperreactivity has been reported in studies using murine models of asthma. In contrast, a clinical study has not found beneficial effects in patients. The rat model of asthma has some distinct...

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Detalhes bibliográficos
Main Authors: Tschernig, Thomas, Bäumer, Wolfgang, Pabst, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047916/
https://ncbi.nlm.nih.gov/pubmed/21437040
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