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Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine.

Intrinsic and acquired multidrug resistance (MDR) is an important problem in cancer therapy. MDR in human KB carcinoma cells selected for resistance to colchicine, vinblastine, or doxorubicin (former generic name adriamycin) is associated with overexpression of the "MDR1" gene, which encod...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ueda, K, Cardarelli, C, Gottesman, M M, Pastan, I
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1987
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC304789/
https://ncbi.nlm.nih.gov/pubmed/3472246
Etiketak: Etiketa erantsi
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