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Induction of synthesis of the cytolytic C9 (ninth component of complement)-related protein in human peripheral mononuclear cells by monoclonal antibody OKT3 or interleukin 2: correlation with cytotoxicity and lymphocyte phenotype.

Synthesis of the cytolytic C9-related protein (C9RP) was induced by activation of resting human peripheral T lymphocytes with the anti-CD3 antibody OKT3 or interleukin 2. Comparison of cellular cytotoxicity and C9RP content at various times during activation yielded a coefficient of correlation r =...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Martin, D E, Zalman, L S, Jung, G, Müller-Eberhard, H J
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1987
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Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304777/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3495005/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.9.2946
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