Vaccines containing purified GM2 ganglioside elicit GM2 antibodies in melanoma patients.

GM2, GD2, and GD3 gangliosides are expressed on the surface of human melanoma cells and represent potential targets for immunological control of melanoma growth by monoclonal antibodies and active immunization. The immunogenicity of GM2 was investigated by analyzing the humoral immune response of me...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Livingston, P O, Natoli, E J, Calves, M J, Stockert, E, Oettgen, H F, Old, L J
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1987
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304770/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3472242/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.9.2911
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