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Renal Safety of a Tenofovir-Containing First Line Regimen: Experience from an Antiretroviral Cohort in Rural Lesotho

INTRODUCTION: Current guidelines contraindicate TDF use when creatinine clearance (CrCl) falls below 50 ml/min. We report prevalence of abnormal renal function at baseline and factors associated with abnormal renal function from a community cohort in Lesotho. METHODS: We calculated changes in CrCl f...

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Main Authors: Bygrave, Helen, Kranzer, Katharina, Hilderbrand, Katherine, Jouquet, Guillaume, Goemaere, Eric, Vlahakis, Nathalie, Triviño, Laura, Makakole, Lipontso, Ford, Nathan
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047584/
https://ncbi.nlm.nih.gov/pubmed/21407815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017609
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