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A Single Base-Pair Change in 2009 H1N1 Hemagglutinin Increases Human Receptor Affinity and Leads to Efficient Airborne Viral Transmission in Ferrets

The 2009 H1N1 influenza A virus continues to circulate among the human population as the predominant H1N1 subtype. Epidemiological studies and airborne transmission studies using the ferret model have shown that the transmission efficiency of 2009 H1N1 viruses is lower than that of previous seasonal...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jayaraman, Akila, Pappas, Claudia, Raman, Rahul, Belser, Jessica A., Viswanathan, Karthik, Shriver, Zachary, Tumpey, Terrence M., Sasisekharan, Ram
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047569/
https://ncbi.nlm.nih.gov/pubmed/21407805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017616
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