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Drosophila Chk2 and p53 proteins induce stage -specific cell death independently during oogenesis
In Drosophila, the checkpoint protein-2 kinase (DmChk2) and its downstream effector protein, Dmp53, are required for DNA damage-mediated cell cycle arrest, DNA repair and apoptosis. In this study we focus on understanding the function of these two apoptosis inducing factors during ovarian developmen...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3047510/ https://ncbi.nlm.nih.gov/pubmed/20838898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-010-0539-z |
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