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Timp-3 deficiency impairs cognitive function in mice

Extracellular matrix (ECM) degradation is performed primarily by matrix metalloproteinases (MMPs). MMPs have recently been shown to regulate synaptic activity in the hippocampus and to affect memory and learning. The tissue inhibitor of metalloproteinase (Timp) is an endogenous factor that controls...

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Detalhes bibliográficos
Main Authors: Baba, Yoshichika, Yasuda, Osamu, Takemura, Yukihiro, Ishikawa, Yasuyuki, Ohishi, Mitsuru, Iwanami, Jun, Mogi, Masaki, Doe, Nobutaka, Horiuchi, Masatsugu, Maeda, Nobuyo, Fukuo, Keisuke, Rakugi, Hiromi
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047444/
https://ncbi.nlm.nih.gov/pubmed/19806081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2009.101
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