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Integration of lipidomics and transcriptomics data towards a systems biology model of sphingolipid metabolism

BACKGROUND: Sphingolipids play important roles in cell structure and function as well as in the pathophysiology of many diseases. Many of the intermediates of sphingolipid biosynthesis are highly bioactive and sometimes have antagonistic activities, for example, ceramide promotes apoptosis whereas s...

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Detalhes bibliográficos
Main Authors: Gupta, Shakti, Maurya, Mano R, Merrill Jr, Alfred H, Glass, Christopher K, Subramaniam, Shankar
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047436/
https://ncbi.nlm.nih.gov/pubmed/21303545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-26
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