CD73 Is Expressed by Human Regulatory T Helper Cells and Suppresses Proinflammatory Cytokine Production and Helicobacter felis–Induced Gastritis in Mice

BACKGROUND: Regulatory T cells (known as “Treg”) express apyrases (CD39) and ecto-5'-nucleotidase (CD73) and contribute to their inhibitory function by generating adenosine. We investigated the expression of CD39 and CD73 on human T helper (Th) cells and the role of CD73 in regulating Helicobac...

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Detalhes bibliográficos
Main Authors: Alam, Mohammad S., Kurtz, Courtney C., Rowlett, Robert M., Reuter, Brian K., Wiznerowicz, Elizabeth, Das, Soumita, Linden, Joel, Crowe, Sheila E., Ernst, Peter B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047419/
https://ncbi.nlm.nih.gov/pubmed/19281303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/596205
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