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In Vivo Measurement of Regional Brain and Tumor pH Using [(14)C]Dimethyloxazolidinedione and Quantitative Autoradiography. II: Characterization of the Extracellular Fluid Compartment Using pH-Sensitive Microelectrodes and [(14)C]Sucrose

We measured the extracellular (interstitial) pH (pH(e)) of RG-2 rat gliomas using H(+) -sensitive micro-electrodes and estimated the volume of tumor extracellular space based on the tissue–plasma ratio of [(14)C]sucrose. The average RG-2 pH(e) was 7.63 ± 0.15 (mean ± SD, n = 6), whereas the average...

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Bibliografische gegevens
Hoofdauteurs: Arnold, James B., Kraig, Richard P., Rottenberg, David A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1986
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047405/
https://ncbi.nlm.nih.gov/pubmed/3733903
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