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Cell- and region-specific miR30-based gene knock-down with temporal control in the rat brain
BACKGROUND: RNA interference (RNAi) emerges as a powerful tool to induce loss-of-function phenotypes. In the context of the brain, gene manipulation is best targeted to specific subsets of cells in order to achieve a physiologically relevant outcome. Polymerase II-based viral expression systems can...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3047298/ https://ncbi.nlm.nih.gov/pubmed/21134262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-11-93 |
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