Soybean-derived Bowman-Birk inhibitor inhibits neurotoxicity of LPS-activated macrophages

BACKGROUND: Lipopolysaccharide (LPS), the major component of the outer membrane of gram-negative bacteria, can activate immune cells including macrophages. Activation of macrophages in the central nervous system (CNS) contributes to neuronal injury. Bowman-Birk inhibitor (BBI), a soybean-derived pro...

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Bibliographic Details
Main Authors: Li, Jieliang, Ye, Li, Cook, Denise R, Wang, Xu, Liu, Jinping, Kolson, Dennis L, Persidsky, Yuri, Ho, Wen-Zhe
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046894/
https://ncbi.nlm.nih.gov/pubmed/21324129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-15
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