Glycosylation Failure Extends to Glycoproteins in Gestational Diabetes Mellitus: Evidence From Reduced α2-6 Sialylation and Impaired Immunomodulatory Activities of Pregnancy-Related Glycodelin-A

OBJECTIVE: Gestational diabetes mellitus (GDM) is a common metabolic disorder of pregnancy. Patients with GDM are at risk for high fetal mortality and gestational complications associated with reduced immune tolerance and abnormal carbohydrate metabolism. Glycodelin-A (GdA) is an abundant decidual g...

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Autori principali: Lee, Cheuk-Lun, Chiu, Philip C.N., Pang, Poh-Choo, Chu, Ivan K., Lee, Kai-Fai, Koistinen, Riitta, Koistinen, Hannu, Seppälä, Markku, Morris, Howard R., Tissot, Bérangère, Panico, Maria, Dell, Anne, Yeung, William S.B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2011
Soggetti:
Pathophysiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046852/
https://ncbi.nlm.nih.gov/pubmed/21300843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1186
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