Differential Lipid Partitioning Between Adipocytes and Tissue Macrophages Modulates Macrophage Lipotoxicity and M2/M1 Polarization in Obese Mice

OBJECTIVE: Obesity-associated insulin resistance is characterized by a state of chronic, low-grade inflammation that is associated with the accumulation of M1 proinflammatory macrophages in adipose tissue. Although different evidence explains the mechanisms linking the expansion of adipose tissue an...

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Detalhes bibliográficos
Main Authors: Prieur, Xavier, Mok, Crystal Y.L., Velagapudi, Vidya R., Núñez, Vanessa, Fuentes, Lucía, Montaner, David, Ishikawa, Ko, Camacho, Alberto, Barbarroja, Nuria, O’Rahilly, Stephen, Sethi, Jaswinder K., Dopazo, Joaquin, Orešič, Matej, Ricote, Mercedes, Vidal-Puig, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2011
Assuntos:
Obesity Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046840/
https://ncbi.nlm.nih.gov/pubmed/21266330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0705
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