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Dual control mechanism for heme oxygenase: tin(IV)-protoporphyrin potently inhibits enzyme activity while markedly increasing content of enzyme protein in liver.

Tin(IV)-protoporphyrin (Sn-protoporphyrin) potently inhibits heme degradation to bile pigments in vitro and in vivo, a property that confers upon this synthetic compound the ability to suppress a variety of experimentally induced and naturally occurring forms of jaundice in animals and humans. Utili...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Sardana, M K, Kappas, A
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1987
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304672/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3470805/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.8.2464
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