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Retroviral-mediated transfer of genomic globin genes leads to regulated production of RNA and protein.

A high-titer amphotropic retroviral vector containing the neomycin resistance gene and a hybrid gamma-beta genomic human globin gene has been constructed. Mouse erythroleukemia cells infected with this virus were found to contain the full transcriptional unit of the transferred human globin gene by...

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Bibliografische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Karlsson, S, Papayannopoulou, T, Schweiger, S G, Stamatoyannopoulos, G, Nienhuis, A W
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1987
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304661/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3470803/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.8.2411
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