Retroviral-mediated transfer of genomic globin genes leads to regulated production of RNA and protein.
A high-titer amphotropic retroviral vector containing the neomycin resistance gene and a hybrid gamma-beta genomic human globin gene has been constructed. Mouse erythroleukemia cells infected with this virus were found to contain the full transcriptional unit of the transferred human globin gene by...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1987
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304661/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3470803/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.8.2411 |
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