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S1 nuclease analysis of alpha-globin gene expression in preleukemic patients with acquired hemoglobin H disease after transfer to mouse erythroleukemia cells.

The loss of alpha-globin gene transcriptional activity rarely occurs as an acquired abnormality during the evolution of myeloproliferative disease or preleukemia. To test whether the mutation responsible for the loss of alpha-globin gene expression (hemoglobin H disease) in these patients is linked...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Helder, J, Deisseroth, A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304656/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3031681/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.8.2387
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