Association between synovial fluid levels of aggrecan ARGS fragments and radiographic progression in knee osteoarthritis

INTRODUCTION: Aggrecanase cleavage at the (392)Glu-(393)Ala bond in the interglobular domain (IGD) of aggrecan, releasing N-terminal (393)ARGS fragments, is an early key event in arthritis and joint injuries. We determined whether synovial fluid (SF) levels of ARGS-aggrecan distinguish subjects with...

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Hauptverfasser: Larsson, Staffan, Englund, Martin, Struglics, André, Lohmander, L Stefan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046543/
https://ncbi.nlm.nih.gov/pubmed/21194461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3217
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