Mapping of citrullinated fibrinogen B-cell epitopes in rheumatoid arthritis by imaging surface plasmon resonance

INTRODUCTION: Rheumatoid arthritis (RA) frequently involves the loss of tolerance to citrullinated antigens, which may play a role in pathogenicity. Citrullinated fibrinogen is commonly found in inflamed synovial tissue and is a frequent target of autoantibodies in RA patients. To obtain insight int...

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Main Authors: van Beers, Joyce JBC, Raijmakers, Reinout, Alexander, Lou-Ella, Stammen-Vogelzangs, Judith, Lokate, Angelique MC, Heck, Albert JR, Schasfoort, Richard BM, Pruijn, Ger JM
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046532/
https://ncbi.nlm.nih.gov/pubmed/21182780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3205
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