A GA microsatellite in the Fli1 promoter modulates gene expression and is associated with systemic lupus erythematosus patients without nephritis

INTRODUCTION: The transcription factor Fli1 is implicated in the pathogenesis of systemic lupus erythematosus (SLE). Recently, a GA(n )polymorphic microsatellite was characterized in the mouse Fli1 promoter that modulates promoter activity and is truncated in two lupus mouse models compared to non-a...

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Bibliografiska uppgifter
Huvudupphovsmän: Morris, Erin E, Amria, May Y, Kistner-Griffin, Emily, Svenson, John L, Kamen, Diane L, Gilkeson, Gary S, Nowling, Tamara K
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2010
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046520/
https://ncbi.nlm.nih.gov/pubmed/21087477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3189
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