Innate but not Adaptive Immune Responses Contribute to Behavioral Seizures Following Viral Infection

PURPOSE: To examine the role of innate immunity in a novel viral infection-induced seizure model. METHODS: C57BL/6 mice, mouse strains deficient in interleukin (IL)-1RI, IL-6, tumor necrosis factor (TNF)-RI, or myeloid differentiation primary response gene 88 (MyD88), or transgenic mice (OT-I) were...

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Bibliographic Details
Main Authors: Kirkman, Nikki J., Libbey, Jane E., Wilcox, Karen S., White, H. Steve, Fujinami, Robert S.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046460/
https://ncbi.nlm.nih.gov/pubmed/19845729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2009.02390.x
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